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Prkn knockout mice show autistic-like behaviors and aberrant synapse formation

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with high genetic heterogeneity, affecting one in 44 children in the United States. Recent genomic sequencing studies from autistic human individuals indicate that PARK2, a gene that has long been considered in the pathogenesis of Parki...

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Detalles Bibliográficos
Autores principales: Huo, Yuda, Lu, Wen, Tian, Yuan, Hou, Qingming, Man, Heng-Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249611/
https://www.ncbi.nlm.nih.gov/pubmed/35789851
http://dx.doi.org/10.1016/j.isci.2022.104573