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Prkn knockout mice show autistic-like behaviors and aberrant synapse formation
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with high genetic heterogeneity, affecting one in 44 children in the United States. Recent genomic sequencing studies from autistic human individuals indicate that PARK2, a gene that has long been considered in the pathogenesis of Parki...
Autores principales: | Huo, Yuda, Lu, Wen, Tian, Yuan, Hou, Qingming, Man, Heng-Ye |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249611/ https://www.ncbi.nlm.nih.gov/pubmed/35789851 http://dx.doi.org/10.1016/j.isci.2022.104573 |
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