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An in vitro human mammary epithelial cell permeability assay to assess drug secretion into breast milk

Determining the amount of a drug transferred into breast milk is critical for benefit-risk analysis of breastfeeding when a lactating mother takes medications. In this study, we developed a human mammary epithelial cell (MEC)-based permeability assay to assess drug permeability across the mammary ep...

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Detalles Bibliográficos
Autores principales: Zhang, Tao, Applebee, Zachary, Zou, Peng, Wang, Zhen, Diaz, Erika Solano, Li, Yanyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249612/
https://www.ncbi.nlm.nih.gov/pubmed/35789754
http://dx.doi.org/10.1016/j.ijpx.2022.100122