Pro-α-cell-derived β-cells contribute to β-cell neogenesis induced by antagonistic glucagon receptor antibody in type 2 diabetic mice

The deficiency of pancreatic β-cells is the key pathogenesis of diabetes, while glucagon-secreting α-cells are another player in the development of diabetes. Here, we aimed to investigate the effects of glucagon receptor (GCGR) antagonism on β-cell neogenesis in type 2 diabetic (T2D) mice and explor...

Descripción completa

Detalles Bibliográficos
Autores principales: Cui, Xiaona, Feng, Jin, Wei, Tianjiao, Gu, Liangbiao, Wang, Dandan, Lang, Shan, Yang, Kun, Yang, Jin, Yan, Hai, Wei, Rui, Hong, Tianpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249614/
https://www.ncbi.nlm.nih.gov/pubmed/35789836
http://dx.doi.org/10.1016/j.isci.2022.104567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249614/
https://www.ncbi.nlm.nih.gov/pubmed/35789836
http://dx.doi.org/10.1016/j.isci.2022.104567

Ejemplares similares