Computational design and engineering of an Escherichia coli strain producing the nonstandard amino acid para-aminophenylalanine

Introducing heterologous pathways into host cells constitutes a promising strategy for synthesizing nonstandard amino acids (nsAAs) to enable the production of proteins with expanded chemistries. However, this strategy has proven challenging, as the expression of heterologous pathways can disrupt ce...

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Detalles Bibliográficos
Autores principales: Zomorrodi, Ali R., Hemez, Colin, Arranz-Gibert, Pol, Wu, Terrence, Isaacs, Farren J., Segrè, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249619/
https://www.ncbi.nlm.nih.gov/pubmed/35789833
http://dx.doi.org/10.1016/j.isci.2022.104562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249619/
https://www.ncbi.nlm.nih.gov/pubmed/35789833
http://dx.doi.org/10.1016/j.isci.2022.104562

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