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Computational design and engineering of an Escherichia coli strain producing the nonstandard amino acid para-aminophenylalanine
Introducing heterologous pathways into host cells constitutes a promising strategy for synthesizing nonstandard amino acids (nsAAs) to enable the production of proteins with expanded chemistries. However, this strategy has proven challenging, as the expression of heterologous pathways can disrupt ce...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249619/ https://www.ncbi.nlm.nih.gov/pubmed/35789833 http://dx.doi.org/10.1016/j.isci.2022.104562 |