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QuantISH: RNA in situ hybridization image analysis framework for quantifying cell type-specific target RNA expression and variability

RNA in situ hybridization (RNA-ISH) is a powerful spatial transcriptomics technology to characterize target RNA abundance and localization in individual cells. This allows analysis of tumor heterogeneity and expression localization, which are not readily obtainable through transcriptomic data analys...

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Detalles Bibliográficos
Autores principales: Jamalzadeh, Sanaz, Häkkinen, Antti, Andersson, Noora, Huhtinen, Kaisa, Laury, Anna, Hietanen, Sakari, Hynninen, Johanna, Oikkonen, Jaana, Carpén, Olli, Virtanen, Anni, Hautaniemi, Sampsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249626/
https://www.ncbi.nlm.nih.gov/pubmed/35169222
http://dx.doi.org/10.1038/s41374-022-00743-5