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Evaluation of parameters for efficient purification and long-term storage of herpes simplex virus-based vectors
Replication competent oncolytic herpes simplex virus (HSV) vectors have been used extensively to treat solid tumors with promising results. However, highly defective HSV vectors will be needed for applications that require sustained therapeutic gene expression in the absence of vector-related toxici...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249677/ https://www.ncbi.nlm.nih.gov/pubmed/35795777 http://dx.doi.org/10.1016/j.omtm.2022.06.007 |