Evaluation of parameters for efficient purification and long-term storage of herpes simplex virus-based vectors

Replication competent oncolytic herpes simplex virus (HSV) vectors have been used extensively to treat solid tumors with promising results. However, highly defective HSV vectors will be needed for applications that require sustained therapeutic gene expression in the absence of vector-related toxici...

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Detalles Bibliográficos
Autores principales: Kuroda, Seiji, Miyagawa, Yoshitaka, Sukegawa, Makoto, Tomono, Taro, Yamamoto, Motoko, Adachi, Kumi, Verlengia, Gianluca, Goins, William F., Cohen, Justus B., Glorioso, Joseph C., Okada, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249677/
https://www.ncbi.nlm.nih.gov/pubmed/35795777
http://dx.doi.org/10.1016/j.omtm.2022.06.007

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