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Filgotinib: A Clinical Pharmacology Review

Filgotinib (GS-6034, formerly GLPG0634; Jyseleca(®)) is an oral, preferential Janus kinase (JAK)-1 inhibitor. Preferential inhibition of JAK1 modulates a subset of proinflammatory cytokines within the JAK–signal transducer and activator of transcription pathway, which differ from those inhibited by...

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Detalles Bibliográficos
Autores principales: Namour, Florence, Anderson, Kacey, Nelson, Cara, Tasset, Chantal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249714/
https://www.ncbi.nlm.nih.gov/pubmed/35637376
http://dx.doi.org/10.1007/s40262-022-01129-y