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Filgotinib: A Clinical Pharmacology Review
Filgotinib (GS-6034, formerly GLPG0634; Jyseleca(®)) is an oral, preferential Janus kinase (JAK)-1 inhibitor. Preferential inhibition of JAK1 modulates a subset of proinflammatory cytokines within the JAK–signal transducer and activator of transcription pathway, which differ from those inhibited by...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249714/ https://www.ncbi.nlm.nih.gov/pubmed/35637376 http://dx.doi.org/10.1007/s40262-022-01129-y |