B cell receptor signaling drives APOBEC3 expression via direct enhancer regulation in chronic lymphocytic leukemia B cells

Constitutively activated B cell receptor (BCR) signaling is a primary biological feature of chronic lymphocytic leukemia (CLL). The biological events controlled by BCR signaling in CLL are not fully understood and need investigation. Here, by analysis of the chromatin states and gene expression prof...

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Detalles Bibliográficos
Autores principales: Wang, Zhiquan, Yan, Huihuang, Boysen, Justin C., Secreto, Charla R., Tschumper, Renee C., Ali, Dania, Guo, Qianqian, Zhong, Jian, Zhou, Jiaqi, Gan, Haiyun, Yu, Chuanhe, Jelinek, Diane F., Slager, Susan L., Parikh, Sameer A., Braggio, Esteban, Kay, Neil E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249768/
https://www.ncbi.nlm.nih.gov/pubmed/35778390
http://dx.doi.org/10.1038/s41408-022-00690-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249768/
https://www.ncbi.nlm.nih.gov/pubmed/35778390
http://dx.doi.org/10.1038/s41408-022-00690-w

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