Mouse pulmonary interstitial macrophages mediate the pro-tumorigenic effects of IL-9

Although IL-9 has potent anti-tumor activity in adoptive cell transfer therapy, some models suggest that it can promote tumor growth. Here, we show that IL-9 signaling is associated with poor outcomes in patients with various forms of lung cancer, and is required for lung tumor growth in multiple mo...

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Detalles Bibliográficos
Autores principales: Fu, Yongyao, Pajulas, Abigail, Wang, Jocelyn, Zhou, Baohua, Cannon, Anthony, Cheung, Cherry Cheuk Lam, Zhang, Jilu, Zhou, Huaxin, Fisher, Amanda Jo, Omstead, David T., Khan, Sabrina, Han, Lei, Renauld, Jean-Christophe, Paczesny, Sophie, Gao, Hongyu, Liu, Yunlong, Yang, Lei, Tighe, Robert M., Licona-Limón, Paula, Flavell, Richard A., Takatsuka, Shogo, Kitamura, Daisuke, Sun, Jie, Bilgicer, Basar, Sears, Catherine R., Yang, Kai, Kaplan, Mark H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249769/
https://www.ncbi.nlm.nih.gov/pubmed/35778404
http://dx.doi.org/10.1038/s41467-022-31596-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249769/
https://www.ncbi.nlm.nih.gov/pubmed/35778404
http://dx.doi.org/10.1038/s41467-022-31596-7

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