Bexarotene-induced cell death in ovarian cancer cells through Caspase-4-gasdermin E mediated pyroptosis

Bexarotene selectively activates retinoid X receptor, which is a commonly used anticancer agent for cutaneous T-cell lymphoma. In this study, we aimed to investigate the anticancer effect of bexarotene and its underlying mechanism in ovarian cancer in vitro. The ES2 and NIH:OVACAR3 ovarian cancer ce...

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Detalles Bibliográficos
Autores principales: Kobayashi, Tatsuya, Mitsuhashi, Akira, Hongying, Piao, Shioya, Masashi, Kojima, Katsushi, Nishikimi, Kyoko, Yahiro, Kinnosuke, Shozu, Makio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249775/
https://www.ncbi.nlm.nih.gov/pubmed/35778597
http://dx.doi.org/10.1038/s41598-022-15348-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249775/
https://www.ncbi.nlm.nih.gov/pubmed/35778597
http://dx.doi.org/10.1038/s41598-022-15348-7

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