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Bexarotene-induced cell death in ovarian cancer cells through Caspase-4-gasdermin E mediated pyroptosis
Bexarotene selectively activates retinoid X receptor, which is a commonly used anticancer agent for cutaneous T-cell lymphoma. In this study, we aimed to investigate the anticancer effect of bexarotene and its underlying mechanism in ovarian cancer in vitro. The ES2 and NIH:OVACAR3 ovarian cancer ce...
Autores principales: | Kobayashi, Tatsuya, Mitsuhashi, Akira, Hongying, Piao, Shioya, Masashi, Kojima, Katsushi, Nishikimi, Kyoko, Yahiro, Kinnosuke, Shozu, Makio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249775/ https://www.ncbi.nlm.nih.gov/pubmed/35778597 http://dx.doi.org/10.1038/s41598-022-15348-7 |
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