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DDX1 vesicles control calcium-dependent mitochondrial activity in mouse embryos
The DEAD box protein DDX1, previously associated with 3’-end RNA processing and DNA repair, forms large aggregates in the cytoplasm of early mouse embryos. Ddx1 knockout causes stalling of embryos at the 2-4 cell stages. Here, we identify a DDX1-containing membrane-bound calcium-containing organelle...
Autores principales: | Wang, Yixiong, Yasmin, Lubna, Li, Lei, Gao, Pinzhang, Xu, Xia, Sun, Xuejun, Godbout, Roseline |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249788/ https://www.ncbi.nlm.nih.gov/pubmed/35778392 http://dx.doi.org/10.1038/s41467-022-31497-9 |
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