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Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria

How bacteria sense and respond to nitrogen levels are central questions in microbial physiology. In Gram-positive bacteria, nitrogen homeostasis is controlled by an operon encoding glutamine synthetase (GS), a dodecameric machine that assimilates ammonium into glutamine, and the GlnR repressor. GlnR...

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Detalles Bibliográficos
Autores principales: Travis, Brady A., Peck, Jared V., Salinas, Raul, Dopkins, Brandon, Lent, Nicholas, Nguyen, Viet D., Borgnia, Mario J., Brennan, Richard G., Schumacher, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249791/
https://www.ncbi.nlm.nih.gov/pubmed/35778410
http://dx.doi.org/10.1038/s41467-022-31573-0