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Transcription factor paralogs orchestrate alternative gene regulatory networks by context-dependent cooperation with multiple cofactors

In eukaryotes, members of transcription factor families often exhibit similar DNA binding properties in vitro, yet orchestrate paralog-specific gene regulatory networks in vivo. The serially homologous first (T1) and third (T3) thoracic legs of Drosophila, which are specified by the Hox proteins Scr...

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Detalles Bibliográficos
Autores principales: Feng, Siqian, Rastogi, Chaitanya, Loker, Ryan, Glassford, William J., Tomas Rube, H., Bussemaker, Harmen J., Mann, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249852/
https://www.ncbi.nlm.nih.gov/pubmed/35778382
http://dx.doi.org/10.1038/s41467-022-31501-2