Oncogenic role and potential regulatory mechanism of topoisomerase IIα in a pan-cancer analysis

Topoisomerase IIα (TOP2A) plays an oncogenic role in multiple tumor types. However, no pan-cancer analysis about the function and the upstream molecular mechanism of TOP2A is available. For the first time, we analyzed potential oncogenic roles of TOP2A in 33 cancer types via The Cancer Genome Atlas...

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Detalles Bibliográficos
Autores principales: Wang, Xiaobo, Wang, Jinhua, Lyu, Li, Gao, Xin, Cai, Yinuo, Tang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249858/
https://www.ncbi.nlm.nih.gov/pubmed/35778520
http://dx.doi.org/10.1038/s41598-022-15205-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249858/
https://www.ncbi.nlm.nih.gov/pubmed/35778520
http://dx.doi.org/10.1038/s41598-022-15205-7

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