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P-glycoprotein: new insights into structure, physiological function, regulation and alterations in disease
The multidrug resistance phenomenon presents a major threat to the pharmaceutical industry. This resistance is a common occurrence in several diseases and is mediated by multidrug transporters that actively pump substances out of the cell and away from their target regions. The most well-known multi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249865/ https://www.ncbi.nlm.nih.gov/pubmed/35789865 http://dx.doi.org/10.1016/j.heliyon.2022.e09777 |