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Amino acid sensor GCN2 promotes SARS-CoV-2 receptor ACE2 expression in response to amino acid deprivation

Angiotensin-converting enzyme 2 (ACE2) has been identified as a primary receptor for severe acute respiratory syndrome coronaviruses 2 (SARS-CoV-2). Here, we investigated the expression regulation of ACE2 in enterocytes under amino acid deprivation conditions. In this study, we found that ACE2 expre...

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Detalles Bibliográficos
Autores principales: Hu, Xiaoming, Niu, Yuguo, Luo, Peixiang, Xiao, Fei, Yuan, Feixiang, Yin, Hanrui, Chen, Shanghai, Guo, Feifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249868/
https://www.ncbi.nlm.nih.gov/pubmed/35778545
http://dx.doi.org/10.1038/s42003-022-03609-0