Core cysteine residues in the Plasminogen-Apple-Nematode (PAN) domain are critical for HGF/c-MET signaling

The Plasminogen-Apple-Nematode (PAN) domain, with a core of four to six cysteine residues, is found in > 28,000 proteins across 959 genera. Still, its role in protein function is not fully understood. The PAN domain was initially characterized in numerous proteins, including HGF. Dysregulation of...

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Detalles Bibliográficos
Autores principales: Pal, Debjani, De, Kuntal, Shanks, Carly M., Feng, Kai, Yates, Timothy B., Morrell-Falvey, Jennifer, Davidson, Russell B., Parks, Jerry M., Muchero, Wellington
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249922/
https://www.ncbi.nlm.nih.gov/pubmed/35778602
http://dx.doi.org/10.1038/s42003-022-03582-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249922/
https://www.ncbi.nlm.nih.gov/pubmed/35778602
http://dx.doi.org/10.1038/s42003-022-03582-8

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