Gene copy number and negative feedback differentially regulate transcriptional variability of segmentation clock genes

Timely progression of a genetic program is critical for embryonic development. However, gene expression involves inevitable fluctuations in biochemical reactions leading to substantial cell-to-cell variability (gene expression noise). One of the important questions in developmental biology is how pa...

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Detalles Bibliográficos
Autores principales: Zinani, Oriana Q.H., Keseroğlu, Kemal, Dey, Supravat, Ay, Ahmet, Singh, Abhyudai, Özbudak, Ertuğrul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250017/
https://www.ncbi.nlm.nih.gov/pubmed/35789861
http://dx.doi.org/10.1016/j.isci.2022.104579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250017/
https://www.ncbi.nlm.nih.gov/pubmed/35789861
http://dx.doi.org/10.1016/j.isci.2022.104579

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