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Slitrk2 deficiency causes hyperactivity with altered vestibular function and serotonergic dysregulation

SLITRK2 encodes a transmembrane protein that modulates neurite outgrowth and synaptic activities and is implicated in bipolar disorder. Here, we addressed its physiological roles in mice. In the brain, the Slitrk2 protein was strongly detected in the hippocampus, vestibulocerebellum, and precerebell...

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Detalles Bibliográficos
Autores principales: Katayama, Kei-ichi, Morimura, Naoko, Kobayashi, Katsunori, Corbett, Danielle, Okamoto, Takehito, Ornthanalai, Veravej G., Matsunaga, Hayato, Fujita, Wakako, Matsumoto, Yoshifumi, Akagi, Takumi, Hashikawa, Tsutomu, Yamada, Kazuyuki, Murphy, Niall P., Nagao, Soichi, Aruga, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250022/
https://www.ncbi.nlm.nih.gov/pubmed/35789858
http://dx.doi.org/10.1016/j.isci.2022.104604