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Stably Integrating an Inducible CRISPR-Cas9 to Protect Against Viral Infections in Vitro
CRISPR-Cas systems protect bacteria from viral nucleic acids. The Cas9 enzyme cleaves bacteriophage DNA preventing viral genes from being expressed in the bacterial host. In this work, the Cas9 protein is repurposed to function as an intracellular mammalian defense mechanism that protects human cell...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Caltech Library
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250034/ https://www.ncbi.nlm.nih.gov/pubmed/35789697 http://dx.doi.org/10.17912/micropub.biology.000590 |