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Negative times negative equals positive, THEMIS sets the rule on thymic selection and peripheral T cell responses

The activity of T cells is finely controlled by a set of negative regulators of T-cell antigen receptor (TCR)-mediated signaling. However, how those negative regulators are themselves controlled to prevent ineffective TCR-mediated responses remain poorly understood. Thymocyte-expressed molecule invo...

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Detalles Bibliográficos
Autores principales: Mélique, Suzanne, Yang, Cui, Lesourne, Renaud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chang Gung University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250082/
https://www.ncbi.nlm.nih.gov/pubmed/35346866
http://dx.doi.org/10.1016/j.bj.2022.03.008