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Negative times negative equals positive, THEMIS sets the rule on thymic selection and peripheral T cell responses
The activity of T cells is finely controlled by a set of negative regulators of T-cell antigen receptor (TCR)-mediated signaling. However, how those negative regulators are themselves controlled to prevent ineffective TCR-mediated responses remain poorly understood. Thymocyte-expressed molecule invo...
Autores principales: | Mélique, Suzanne, Yang, Cui, Lesourne, Renaud |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chang Gung University
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250082/ https://www.ncbi.nlm.nih.gov/pubmed/35346866 http://dx.doi.org/10.1016/j.bj.2022.03.008 |
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