Transient early life growth hormone exposure permanently alters brain, muscle, liver, macrophage, and adipocyte status in long‐lived Ames dwarf mice

The exceptional longevity of Ames dwarf (DF) mice can be abrogated by a brief course of growth hormone (GH) injections started at 2 weeks of age. This transient GH exposure also prevents the increase in cellular stress resistance and decline in hypothalamic inflammation characteristic of DF mice. He...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xinna, McPherson, Madaline, Hager, Mary, Fang, Yimin, Bartke, Andrzej, Miller, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250136/
https://www.ncbi.nlm.nih.gov/pubmed/35704312
http://dx.doi.org/10.1096/fj.202200143R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250136/
https://www.ncbi.nlm.nih.gov/pubmed/35704312
http://dx.doi.org/10.1096/fj.202200143R

Ejemplares similares