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Circular RNA EIF4G3 suppresses gastric cancer progression through inhibition of β-catenin by promoting δ-catenin ubiquitin degradation and upregulating SIK1

BACKGROUND: Increasing studies suggest that circular RNAs (circRNAs) are critical regulators of cancer development and progression. However, the biological roles and mechanisms of circRNAs in gastric cancer (GC) remain largely unknown. METHODS: We identified the differentially expressed circRNAs in...

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Detalles Bibliográficos
Autores principales: Zang, Xueyan, Jiang, Jiajia, Gu, Jianmei, Chen, Yanke, Wang, Maoye, Zhang, Yu, Fu, Min, Shi, Hui, Cai, Hui, Qian, Hui, Xu, Wenrong, Zhang, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250212/
https://www.ncbi.nlm.nih.gov/pubmed/35780119
http://dx.doi.org/10.1186/s12943-022-01606-9