Enhanced protein translocation to mammalian cells by expression of EtgA transglycosylase in a synthetic injector E. coli strain

BACKGROUND: Bacterial type III secretion systems (T3SSs) assemble a multiprotein complex termed the injectisome, which acts as a molecular syringe for translocation of specific effector proteins into the cytoplasm of host cells. The use of injectisomes for delivery of therapeutic proteins into mamma...

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Detalles Bibliográficos
Autores principales: Álvarez, Beatriz, Muñoz-Abad, Víctor, Asensio-Calavia, Alejandro, Fernández, Luis Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250224/
https://www.ncbi.nlm.nih.gov/pubmed/35780105
http://dx.doi.org/10.1186/s12934-022-01860-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250224/
https://www.ncbi.nlm.nih.gov/pubmed/35780105
http://dx.doi.org/10.1186/s12934-022-01860-y

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