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Proteomics-based investigation of cerebrovascular molecular mechanisms in cerebral amyloid angiopathy by the FFPE-LMD-PCT-SWATH method

BACKGROUND: Cerebral amyloid angiopathy (CAA) occurs in 80% of patients with Alzheimer’s disease (AD) and is mainly caused by the abnormal deposition of Aβ in the walls of cerebral blood vessels. Cerebrovascular molecular mechanisms in CAA were investigated by using comprehensive and accurate quanti...

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Detalles Bibliográficos
Autores principales: Handa, Takumi, Sasaki, Hayate, Takao, Masaki, Tano, Mitsutoshi, Uchida, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250250/
https://www.ncbi.nlm.nih.gov/pubmed/35778717
http://dx.doi.org/10.1186/s12987-022-00351-x