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Appropriate Dose of Dapagliflozin Improves Cardiac Outcomes by Normalizing Mitochondrial Fission and Reducing Cardiomyocyte Apoptosis After Acute Myocardial Infarction

OBJECTIVE: Dapagliflozin (DAPA) has been reported to have significant cardiac protective effects on heart failure (HF). However, the dose and time, as well as the underlying mechanisms, for DAPA treatment in acute myocardial infarction (AMI) remain controversial. The aim of this study aimed to asses...

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Detalles Bibliográficos
Autores principales: Fan, Zhong-guo, Xu, Yang, Chen, Xi, Ji, Ming-yue, Ma, Gen-shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250321/
https://www.ncbi.nlm.nih.gov/pubmed/35789742
http://dx.doi.org/10.2147/DDDT.S371506