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HIV-1 exploits the Fanconi anemia pathway for viral DNA integration

The integration of HIV-1 DNA into the host genome results in single-strand gaps and 2-nt overhangs at the ends of viral DNA, which must be repaired by cellular enzymes. The cellular factors responsible for the DNA damage repair in HIV-1 DNA integration have not yet been well defined. We report here...

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Detalles Bibliográficos
Autores principales: Fu, Shaozu, Phan, An Thanh, Mao, Dexin, Wang, Xinlu, Gao, Guangxia, Goff, Stephen P., Zhu, Yiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250337/
https://www.ncbi.nlm.nih.gov/pubmed/35613597
http://dx.doi.org/10.1016/j.celrep.2022.110840