Up-regulation of the Cdc42 GTPase limits the replicative life span of budding yeast

Cdc42, a conserved Rho GTPase, plays a central role in polarity establishment in yeast and animals. Cell polarity is critical for asymmetric cell division, and asymmetric cell division underlies replicative aging of budding yeast. Yet how Cdc42 and other polarity factors impact life span is largely...

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Detalles Bibliográficos
Autores principales: Kang, Pil Jung, Mullner, Rachel, Li, Haoyu, Hansford, Derek, Shen, Han-Wei, Park, Hay-Oak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250358/
https://www.ncbi.nlm.nih.gov/pubmed/35044837
http://dx.doi.org/10.1091/mbc.E21-04-0208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250358/
https://www.ncbi.nlm.nih.gov/pubmed/35044837
http://dx.doi.org/10.1091/mbc.E21-04-0208

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