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Phylogenetic profiling and cellular analyses of ARL16 reveal roles in traffic of IFT140 and INPP5E

The ARF family of regulatory GTPases is ancient, with 16 members predicted to have been present in the last eukaryotic common ancestor. Our phylogenetic profiling of paralogues in diverse species identified four family members whose presence correlates with that of a cilium/flagellum: ARL3, ARL6, AR...

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Detalles Bibliográficos
Autores principales: Dewees, Skylar I., Vargová, Romana, Hardin, Katherine R., Turn, Rachel E., Devi, Saroja, Linnert, Joshua, Wolfrum, Uwe, Caspary, Tamara, Eliáš, Marek, Kahn, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250359/
https://www.ncbi.nlm.nih.gov/pubmed/35196065
http://dx.doi.org/10.1091/mbc.E21-10-0509-T