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A systems approach to investigate GPCR-mediated Ras signaling network in chemoattractant sensing

A GPCR-mediated signaling network enables a chemotactic cell to generate adaptative Ras signaling in response to a large range of concentrations of a chemoattractant. To explore potential regulatory mechanisms of GPCR-controlled Ras signaling in chemosensing, we applied a software package, Simmune,...

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Detalles Bibliográficos
Autores principales: Xu, Xuehua, Quan, Wei, Zhang, Fengkai, Jin, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250378/
https://www.ncbi.nlm.nih.gov/pubmed/34910560
http://dx.doi.org/10.1091/mbc.E20-08-0545