Nir1 constitutively localizes at ER–PM junctions and promotes Nir2 recruitment for PIP(2) homeostasis

Homeostatic regulation of plasma membrane (PM) phosphatidylinositol 4,5-bisphosphate (PIP(2)) in receptor-stimulated cells is mediated by the lipid transfer protein Nir2. Nir2 is dynamically recruited to endoplasmic reticulum–plasma membrane (ER–PM) junctions to facilitate replenishment of PM PIP(2)...

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Detalles Bibliográficos
Autores principales: Quintanilla, Carlo Giovanni, Lee, Wan-Ru, Liou, Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250379/
https://www.ncbi.nlm.nih.gov/pubmed/35020418
http://dx.doi.org/10.1091/mbc.E21-07-0356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250379/
https://www.ncbi.nlm.nih.gov/pubmed/35020418
http://dx.doi.org/10.1091/mbc.E21-07-0356

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