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Endoplasmic reticulum–to–Golgi trafficking of procollagen III via conventional vesicular and tubular carriers

Collagen is the major protein component of the extracellular matrix. Synthesis of procollagens starts in the endoplasmic reticulum (ER), and three α chains form a rigid triple helix 300–400 nm in length. It remains unclear how such a large cargo is transported from the ER to the Golgi apparatus. In...

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Detalles Bibliográficos
Autores principales: Hirata, Yukihiro, Matsui, Yuto, Wada, Ikuo, Hosokawa, Nobuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250382/
https://www.ncbi.nlm.nih.gov/pubmed/35044867
http://dx.doi.org/10.1091/mbc.E21-07-0372