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An in situ hydrogel-mediated chemo-immunometabolic cancer therapy

Metabolic reprogramming of the tumor microenvironment (TME) and poor immunogenicity are two of the challenges that cancer immunotherapies have to overcome for improved clinical benefits. Among various immunosuppressive metabolites that keep anti-tumor immunity in check, the tryptophan catabolite kyn...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Chen, Jing, Caserto, Julia S., Wang, Xi, Ma, Minglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250515/
https://www.ncbi.nlm.nih.gov/pubmed/35780226
http://dx.doi.org/10.1038/s41467-022-31579-8