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Heterozygous LMNA mutation-carrying iPSC lines from three cardiac laminopathy patients

LMNA-related dilated cardiomyopathy (LMNA-DCM) is caused by pathogenic variants in the LMNA gene and is characterized by left ventricular chamber enlargement, reduced systolic function, and arrhythmia. Here, we generated three human induced pluripotent stem cell (iPSC) lines from peripheral blood mo...

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Detalles Bibliográficos
Autores principales: Cho, Sangkyun, Lee, Chelsea, Lai, Celine, Zhuge, Yan, Haddad, Francois, Fowler, Michael, Sallam, Karim, Wu, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250545/
https://www.ncbi.nlm.nih.gov/pubmed/34999423
http://dx.doi.org/10.1016/j.scr.2022.102657