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APEX1 regulates alternative splicing of key tumorigenesis genes in non-small-cell lung cancer

BACKGROUND: Aberrant alternative splicing (AS) contributes to tumor progression. Previous studies have shown that apurinic-apyrimidinic endonuclease-1 (APEX1) is involved in tumor progression. It is unknown whether APEX1 functions in tumor progression by regulation of AS. It is also unknown whether...

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Detalles Bibliográficos
Autores principales: Peng, Li, Liu, Yuwei, Chen, Jing, Cheng, Mengxin, Wu, Ying, Chen, Min, Zhong, Ya, Shen, Dan, Chen, Ling, Ye, Xujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250739/
https://www.ncbi.nlm.nih.gov/pubmed/35780128
http://dx.doi.org/10.1186/s12920-022-01290-0