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Reduced frequencies of Foxp3(+)GARP(+) regulatory T cells in COPD patients are associated with multi-organ loss of tissue phenotype

BACKGROUND: Expression of glycoprotein A dominant repeat (GARP) has been reported to occur only in activated human naturally occurring regulatory T cells (Tregs) and their clones, and not in activated effector T cells, indicating that GARP is a marker for bona fide Tregs. A different phenotype of ch...

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Detalles Bibliográficos
Autores principales: Hou, Jia, Wang, Xia, Su, Chunxia, Ma, Weirong, Zheng, Xiwei, Ge, Xiahui, Duan, Xiangguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250745/
https://www.ncbi.nlm.nih.gov/pubmed/35780120
http://dx.doi.org/10.1186/s12931-022-02099-2