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Reduced frequencies of Foxp3(+)GARP(+) regulatory T cells in COPD patients are associated with multi-organ loss of tissue phenotype
BACKGROUND: Expression of glycoprotein A dominant repeat (GARP) has been reported to occur only in activated human naturally occurring regulatory T cells (Tregs) and their clones, and not in activated effector T cells, indicating that GARP is a marker for bona fide Tregs. A different phenotype of ch...
Autores principales: | Hou, Jia, Wang, Xia, Su, Chunxia, Ma, Weirong, Zheng, Xiwei, Ge, Xiahui, Duan, Xiangguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250745/ https://www.ncbi.nlm.nih.gov/pubmed/35780120 http://dx.doi.org/10.1186/s12931-022-02099-2 |
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