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Spike-mediated ACE2 down-regulation was involved in the pathogenesis of SARS-CoV-2 infection

The ongoing global pandemic of Coronavirus disease 2019 (COVID-19) poses a serious threat to human health, with patients reportedly suffering from thrombus, vascular injury and coagulation in addition to acute and diffuse lung injury and respiratory diseases. Angiotensin converting enzyme 2 (ACE2) a...

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Detalles Bibliográficos
Autores principales: Gao, Xiang, Zhang, Shengyuan, Gou, Jizhou, Wen, Yanling, Fan, Lujie, Zhou, Jian, Zhou, Guangde, Xu, Gang, Zhang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd on behalf of The British Infection Association. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250808/
https://www.ncbi.nlm.nih.gov/pubmed/35793758
http://dx.doi.org/10.1016/j.jinf.2022.06.030