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Chalcone-amide, a privileged backbone for the design and development of selective SARS-CoV/SARS-CoV-2 papain-like protease inhibitors
The newly emerged coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that caused the COVID-19 pandemic, is the closest relative of SARS-CoV with high genetic similarity. The papain-like protease (PLpro) is an important SARS-CoV/SARS-CoV-2 nonstructural protein that plays a crit...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier Masson SAS.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250826/ https://www.ncbi.nlm.nih.gov/pubmed/35797899 http://dx.doi.org/10.1016/j.ejmech.2022.114572 |