Cargando…
The role of lipid components in lipid nanoparticles for vaccines and gene therapy
Lipid nanoparticles (LNPs) play an important role in mRNA vaccines against COVID-19. In addition, many preclinical and clinical studies, including the siRNA-LNP product, Onpattro®, highlight that LNPs unlock the potential of nucleic acid-based therapies and vaccines. To understand what is key to the...
Autores principales: | Hald Albertsen, Camilla, Kulkarni, Jayesh A., Witzigmann, Dominik, Lind, Marianne, Petersson, Karsten, Simonsen, Jens B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250827/ https://www.ncbi.nlm.nih.gov/pubmed/35787388 http://dx.doi.org/10.1016/j.addr.2022.114416 |
Ejemplares similares
-
mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability
por: Schoenmaker, Linde, et al.
Publicado: (2021) -
Lipid nanoparticle technology for therapeutic gene regulation in the liver
por: Witzigmann, Dominik, et al.
Publicado: (2020) -
Lipid Nanoparticle-Mediated
Hit-and-Run Approaches
Yield Efficient and Safe In Situ Gene Editing in
Human Skin
por: Bolsoni, Juliana, et al.
Publicado: (2023) -
Lipid Constituents of Diatoms (Halamphora) as Components for Production of Lipid Nanoparticles
por: Marzec, Marta, et al.
Publicado: (2022) -
Lipid nanoparticle mRNA systems containing high levels of sphingomyelin engender higher protein expression in hepatic and extra-hepatic tissues
por: Chander, Nisha, et al.
Publicado: (2023)