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An integrated biomarker of PD‐L1 expression and intraepithelial CD8 (+) T cell infiltration was associated with the prognosis of lung cancer patients after intracranial resection of brain metastases

BACKGROUND: Brain metastases (BM) are common in lung cancer. However, data on the status of immune biomarkers in BM lesions remain limited. METHODS: We retrospectively analyzed PD‐L1 expression and infiltration levels of CD3(+), CD4(+), CD8(+) T cells as biomarkers by immunohistochemistry in both BM...

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Detalles Bibliográficos
Autores principales: Li, Lin‐Lin, Zhou, De‐Xiang, Lu, Ming, Zhou, Dong, Lin, Xiao‐Feng, Chen, Yu, Yin, Kai, Feng, Hui‐Bo, Guo, Wei‐Bang, Xie, Zhi, Yan, Wen‐Qing, Lv, Zhi‐Yi, Lu, Dan‐Xia, Zhang, Shui‐Lian, Zhang, Xu‐Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250837/
https://www.ncbi.nlm.nih.gov/pubmed/35596539
http://dx.doi.org/10.1111/1759-7714.14473