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Evaluation of Immunoproteasome-Specific Proteolytic Activity Using Fluorogenic Peptide Substrates

The 26S proteasome irreversibly hydrolyzes polyubiquitylated substrates to maintain protein homeostasis; it also regulates immune responses by generating antigenic peptides. An alternative form of the 26S proteasome is the immunoproteasome, which contains substituted catalytic subunits (β1i/PSMB9, β...

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Detalles Bibliográficos
Autores principales: Kim, Sumin, Park, Seo Hyeong, Choi, Won Hoon, Lee, Min Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250865/
https://www.ncbi.nlm.nih.gov/pubmed/35799704
http://dx.doi.org/10.4110/in.2022.22.e28