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Polo-Like Kinase 1 Regulates Chromosomal Instability and Paclitaxel Resistance in Breast Cancer Cells

PURPOSE: Chromosomal instability (CIN) contributes to intercellular genetic heterogeneity and has been implicated in paclitaxel (PTX) resistance in breast cancer. In this study, we explored polo-like kinase 1 (PLK1) as an important regulator of mitotic integrity and as a useful predictive biomarker...

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Detalles Bibliográficos
Autores principales: Quan, Mingji, Oh, Yumi, Cho, Sung-Yup, Kim, Ju Hee, Moon, Hyeong-Gon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Breast Cancer Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250878/
https://www.ncbi.nlm.nih.gov/pubmed/35775700
http://dx.doi.org/10.4048/jbc.2022.25.e28