Cargando…

Polo-Like Kinase 1 Regulates Chromosomal Instability and Paclitaxel Resistance in Breast Cancer Cells

PURPOSE: Chromosomal instability (CIN) contributes to intercellular genetic heterogeneity and has been implicated in paclitaxel (PTX) resistance in breast cancer. In this study, we explored polo-like kinase 1 (PLK1) as an important regulator of mitotic integrity and as a useful predictive biomarker...

Descripción completa

Detalles Bibliográficos
Autores principales:	Quan, Mingji, Oh, Yumi, Cho, Sung-Yup, Kim, Ju Hee, Moon, Hyeong-Gon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Breast Cancer Society 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250878/ https://www.ncbi.nlm.nih.gov/pubmed/35775700 http://dx.doi.org/10.4048/jbc.2022.25.e28

Ejemplares similares

Putting a bit into the polo-box domain of polo-like kinase 1
por: Park, Jung-Eun, et al.
Publicado: (2015)

Polo-like kinase in trypanosomes: an odd member out of the Polo family
por: Kurasawa, Yasuhiro, et al.
Publicado: (2020)

Targeting Polo-like kinase in space and time during C. elegans meiosis
por: Brandt, James N., et al.
Publicado: (2021)

The Chromosomal Passenger Complex Activates Polo Kinase at Centromeres
por: Carmena, Mar, et al.
Publicado: (2012)

Spatial and temporal control of targeting Polo-like kinase during meiotic prophase
por: Brandt, James N., et al.
Publicado: (2020)

Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1
por: Yun, Sang-Moon, et al.
Publicado: (2009)

A cryptic hydrophobic pocket in the polo-box domain of the polo-like kinase PLK1 regulates substrate recognition and mitotic chromosome segregation
por: Sharma, Pooja, et al.
Publicado: (2019)

The balance of Polo-like kinase 1 in tumorigenesis
por: Lu, Lin-Yu, et al.
Publicado: (2009)

The CINs of Polo-Like Kinase 1 in Cancer
por: Cunningham, Chelsea E., et al.
Publicado: (2020)

Correction: The Chromosomal Passenger Complex Activates Polo Kinase at Centromeres
por: Carmena, Mar, et al.
Publicado: (2012)

Polo-like kinase-1 in DNA damage response
por: Hyun, Sun-Yi, et al.
Publicado: (2014)

Polo-like kinase 1 as target for cancer therapy
por: Weiß, Lily, et al.
Publicado: (2012)

Playing POLO-like kinase in NRAS mutant melanoma
por: Chen, Hsin-Yi, et al.
Publicado: (2015)

Role for polo-like kinase 4 in mediation of cytokinesis
por: Press, Michael F., et al.
Publicado: (2019)

Polo-Like Kinase 2: From Principle to Practice
por: Zhang, Chuanyong, et al.
Publicado: (2022)

Polo-like kinase 1 promotes pulmonary hypertension
por: Chen, Rongrong, et al.
Publicado: (2023)

A selective inhibitor of the Polo-box domain of Polo-like kinase 1 identified by virtual screening
por: Abdelfatah, Sara, et al.
Publicado: (2018)

Polo-like kinase 1 is involved in apoptosis, invasion, and metastasis of pancreatic ductal adenocarcinoma
por: Mao, Yonghuan, et al.
Publicado: (2020)

Exploring the Binding Nature of Pyrrolidine Pocket-Dependent Interactions in the Polo-Box Domain of Polo-Like Kinase 1
por: Murugan, Ravichandran N., et al.
Publicado: (2013)

Identification of a novel Polo-like kinase 1 inhibitor that specifically blocks the functions of Polo-Box domain
por: Chen, Yunyu, et al.
Publicado: (2016)

Polo-Like Kinase Controls Vertebrate Spindle Elongation and Cytokinesis
por: Brennan, Ian M., et al.
Publicado: (2007)

Polo-like kinase 4: the odd one out of the family
por: Sillibourne, James E, et al.
Publicado: (2010)

Roles of Polo-like kinase 3 in suppressing tumor angiogenesis
por: Xu, Dazhong, et al.
Publicado: (2012)

Enhanced polo-like kinase 1 expression in myelodysplastic syndromes
por: Min, Kyoung Il, et al.
Publicado: (2019)

Therapeutic inhibition of polo‐like kinases in anaplastic thyroid cancer
por: Lin, Shu‐Fu, et al.
Publicado: (2021)

Chemical Probe for Imaging of Polo-like Kinase 4 and Centrioles
por: Salim, Aleksandar, et al.
Publicado: (2023)

Physical Association of Saccharomyces cerevisiae Polo-like Kinase Cdc5 with Chromosomal Cohesin Facilitates DNA Damage Response
por: Pakchuen, Sujiraporn, et al.
Publicado: (2016)

Inhibition of Polo-like kinase 1 reduces beta-amyloid-induced neuronal cell death in Alzheimer's disease
por: Song, Bing, et al.
Publicado: (2011)

Mitosis-specific phosphorylation of Mis18α by Aurora B kinase enhances kinetochore recruitment of polo-like kinase 1
por: Lee, Minkyoung, et al.
Publicado: (2017)

Design and Synthesis of a Cell-Permeable, Drug-Like Small Molecule Inhibitor Targeting the Polo-Box Domain of Polo-Like Kinase 1
por: Srinivasrao, Ganipisetti, et al.
Publicado: (2014)

Polo-like kinase 4 controls centriole duplication but does not directly regulate cytokinesis
por: Holland, Andrew J., et al.
Publicado: (2012)

Co-inhibition of polo-like kinase 1 and Aurora kinases promotes mitotic catastrophe
por: Li, Jingjing, et al.
Publicado: (2015)

Synthetic Strategies of Pyrimidine-Based Scaffolds as Aurora Kinase and Polo-like Kinase Inhibitors
por: Jadhav, Mrunal, et al.
Publicado: (2021)

Polo-like kinase is required for Golgi and bilobe biogenesis in Trypanosoma brucei
por: de Graffenried, Christopher L., et al.
Publicado: (2008)

Autophosphorylation of Polo-like Kinase 4 and Its Role in Centriole Duplication
por: Sillibourne, James E., et al.
Publicado: (2010)

NFκB regulates expression of Polo-like kinase 4
por: Ledoux, Adeline C, et al.
Publicado: (2013)

Discovery and development of the Polo-like kinase inhibitor volasertib in cancer therapy
por: Gjertsen, B T, et al.
Publicado: (2015)

Linear Regression QSAR Models for Polo-Like Kinase-1 Inhibitors
por: Duchowicz, Pablo R.
Publicado: (2018)

Inhibition of Prostate Smooth Muscle Contraction by Inhibitors of Polo-Like Kinases
por: Hennenberg, Martin, et al.
Publicado: (2018)

A Perspective on Polo-Like Kinase-1 Inhibition for the Treatment of Rhabdomyosarcomas
por: Gatz, Susanne A., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_agaa4qt6ru0khftbh96a7b9g82