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靶向CD33抗原三特异性T细胞衔接器的制备及对白血病细胞的作用研究
OBJECTIVE: To investigate the effect of CD33-targeted bi-specific and tri-specific T-cell engagers on T-cell proliferation and explore their cytotoxicity on leukemia cells. METHODS: The CD33-targeted bi-specific T-cell engager(CD33-BiTE)and tri-specific T-cell engager(CD33-TriTE)expression vectors w...
Formato: | Online Artículo Texto |
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Lenguaje: | English |
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Editorial office of Chinese Journal of Hematology
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250957/ https://www.ncbi.nlm.nih.gov/pubmed/35680594 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2022.05.005 |