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靶向CD33抗原三特异性T细胞衔接器的制备及对白血病细胞的作用研究

OBJECTIVE: To investigate the effect of CD33-targeted bi-specific and tri-specific T-cell engagers on T-cell proliferation and explore their cytotoxicity on leukemia cells. METHODS: The CD33-targeted bi-specific T-cell engager(CD33-BiTE)and tri-specific T-cell engager(CD33-TriTE)expression vectors w...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9250957/
https://www.ncbi.nlm.nih.gov/pubmed/35680594
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2022.05.005